Albendazol

Albendazol

Albendazol CAS:54965-21-8

Albendazol Chemical Properties

MF: C12H15N3O2S

MW: 265,33

EINECS: 259-414-7

Tališče: 208-210 ° c

Gostota: 1,2561 (groba ocena)

Lomni količnik: 1,6740 (ocena)

Topnost: praktično netopen v vodi, dobro topen v brezvodni mravljični kislini, zelo slabo topen v metilen kloridu, praktično netopen v etanolu (96 odstotkov).

Pka: 10,72 ± 0,10 (predvidena)

Topnost v vodi: 0,75 mg / L (209 ° C)

Albendazol CAS:54965-21-8 Specifikacija:

Albendazol CAS:54965-21-8 Introduction:

1. Albendazol is a kind of broad spectrum thiabendazole class anthelmintics which can be applied by both human and animal.

2. Albendazol can inhibit the parasite growth and reproduction by inhibiting the intestinal and absorbing the intracellular protein, resulting in the failure of parasite in sugar uptake which is indispensable for their survival, thus causing the endogenous glycogen depletion of insects and further inhibiting fumarate reductase system, preventing the generation of adenosine triphosphate, causing that the parasites are not be able to further survive and reproduce, and ultimately die due to energy depletion.

Albendazol CAS:54965-21-8 Functions

Albendazol is an anthelmintic or anti- worm medication. It prevents newly hatched insect larvae (worms) from growing or multiplying in your body.  

Albendazol is used to treat certain infections caused by worms such as pork tapeworm and dog tapeworm.

1. Albendazol is highly effective broad spectrum anthelmintic drugs, is benzimidazole deworming drugs in the broader spectrum.

2. Albendazol is highly active against nematodes, schistosomes, tapeworms, but also significantly inhibited the development of eggs.

3. Albendazol on parasitic nematodes in a variety of animals, schistosomes, tapeworms and cysticerci also has a significant role in repelling.

4. Albendazol is applied to get rid of roundworm, pinworm, hookworm, whipworm, can also be used for deworming livestock.

Albendazol CAS:54965-21-8 Application:

1. Širokospektralni antiparazitik; Uporablja se za izgon ogorčic, trakulj, trematodnih črvov in ektoparazitov pri živini.

2. Albendazol has a broad spectrum of insect repellents, and has a strong effect on nematode, tapeworm and trematode; Its mechanism of action is to bind to microtubulin in the worm and prevent it polymerize withα-tubulin to form microtubules, thus affecting cell reproduction processes such as mitosis, protein assembly and energy metabolism.

3. Ivermektin dobro vpliva na notranje in zunanje zajedavce, zlasti žuželke členonožce in notranje črve ogorčic; Uporablja se predvsem za izgon prebavil ogorčic, pljuč in ektoparazitov; Mehanizem razglistavanja je pospeševanje sproščanja GABA s strani presinaptičnih nevronov, s čimer se odpirajo kanali kloridnih ionov, posredovani z GABA; Pretok klorovih ionov lahko zmanjša odpornost celične membrane, povzroči rahlo depolarizacijo statičnega potenciala postsinaptične membrane, moti prenos signala med živčnimi mišicami in povzroči, da se telo žuželk sprosti in ohromi, kar povzroči smrt ali izgon telo žuželk.