Fenacetin je bel, z bleščečimi luskasti kristali ali belim kristaliničnim prahom, brez vonja, rahlo grenak okus. Ta izdelek je raztopljen v etanolu ali kloroformu, rahlo raztopljen v vreli vodi in zelo rahlo raztopljen v vodi
Fenacetin
Fenacetin CAS:62-44-2
Fenacetin Chemical Properties
MF: C10H13NO2
MW: 179,22
Tališče: 133-136 ° C (prižgano)
Vrelišče: 132 ° C / 4mmHg
Gostota: 1.1248 (groba ocena)
Fenacetin Specification:
Analiza% â ‰ ¥ 99,0
% organskega klorida â ‰ ¤ 0,02
p-Phenetidine ‰ ¤ light redã € 4 #
Enostavna ogljikova zmesâ ‰ ¤4 # ã € 6 #
Izguba pri sušenju% â ‰ ¤0,5
Tališče: 134-137 ° C
Vžigalni ostanek% â ‰ ¤ 0,1
Fenacetin Introduction:
Fenacetin is a non-opioid analgesic without anti-inflammatory properties, inhibits COX-3 activity.Target: COXFenacetin is a pain-relieving and fever-reducing drug,
Fenacetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy. the clinical and laboratory data were compatible with“phenacetin nephritis”as described in Europe and Australia and recently in the United States and Canada.
This report evaluates the findings in the 23 cases and cautions against the use of phenacetin, particularly in patients with impaired renal function [1]. Fenacetin has been linked to renal papillary necrosis in human beings [2, 3].
Fenacetin Application:
Antipiretični analgetik, ki se uporablja za zdravljenje vročine, glavobola, nevralgije itd
